By Mark Ptashne – A Genetic Switch: Phage Lambda Revisited: 3rd (third) Edition [Mark Ptashne] on *FREE* shipping on qualifying offers. The first edition of Mark Ptashne’s book describing the principles of gene regulation in phage lambda became a classic in both content and form, setting a . A genetic switch: Gene control and phage λ. by Mark Ptashne, Cell Press and Blackwell Scientific Publications, £ (x + pages) ISBN 0

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Would you like to tell us about a lower price? If you are a seller for this product, would you like to suggest updates through seller support? The first edition of Mark Ptashne’s book describing the principles of gene regulation in phage lambda geneyic a classic in both content and form, setting a standard of clarity and precise venetic that has rarely been bettered.

This edition is a reprint of the original text, together with a new chapter updating the story to Among the striking new developments are recent findings on long-range interactions between proteins bound to widely separated sites on the phage genome, and a detailed description of how gene activation works. Read more Read less.

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A Genetic Switch: Gene Control and Phage Lambda

Buy the selected items together This item: A Genetic Switch, Third Edition: Ships from and sold by Amazon. Developmental Biology by Scott F. Sold by 1BooksOutlet and ships from Amazon Fulfillment. Customers who bought this item also bought.

Page 1 of 1 Start over Page 1 of 1. Viruses, Plagues, and History: Past, Present and Future. Fundamentals of Molecular Virology. The Eighth Day of Creation: Makers of the Revolution in Biology, Commemorative Edition. Don’t have a Kindle? Try the Kindle edition and experience these great reading features: Share your thoughts with other customers. maark

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Kindle Edition Verified Purchase. One person found this helpful. This classic text explains the structure and function of an epigenetic switch employed by the incredibly simple genome of a common virus. It reads like a code review of an ingenious piece of software. It starts with gfnetic high level overview and iterates to reveal more detail.

Every detail is then traced back to an actual reproducible experiment. So at the end we don’t only know how the phage works, but also how we know it.

The Kindle version does have a few typesetting problems that interfere mildly with comprehension of the material. This book details the mechanism and presents the supporting data for the paradigm of bacterial gene regulation, the bacteriophage lambda repressor. What sets this book apart is not just the subject matter, but the clarity of Ptashne’s writing and the superb illustrations that accompany his text.

The combination of the two make the book useful for graduate students but also accessible for the general reader with an interest in science.

Whenever new people join my laboratory, I have them read this book. Excellent title that sheds some light on how life, or not-life like viruses, works. You can read this prashne even if you are not a biologist, or if you have almost no scientific background. True, you might need to resort sometimes to Wikipedia in the later case, but you will likely gain something.

Its also, in general, a beautiful example of gene regulation-a perfect heist story of a cell. I found out about this unassuming little book in Sean Carroll’s “Endless forms most beautiful” and was delighted. When I first started reading it, a stranger who saw me with it smiled and I soon found out why. It can be read by anyone with a modest scientific education little more than high school but it takes you up to the frontiers of research on gene regulation.

Readers who remember the way “Scientific American” used to cover molecular biology in ‘s through the ’80’s or have read reprints from that era will appreciate the highly visual style and the clear prose. The genetic switch in question determines gehetic the genes of ptashen virus that infects a bacterial cell will quietly integrate themselves into the bacterial genome and be copied along with the bacteria’s genes each time the cell divides or use the cell’s machinery to make many copies of itself, quickly destroying the cell in the process.


If you are like me you’ll be fascinated to learn how this switch works and about the experiments that revealed its secrets. Quick read, very thorough and very interesting. See all 7 reviews. Amazon Giveaway allows you to run promotional giveaways in order to create buzz, reward your audience, and attract new followers and customers.

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A Genetic Switch, Third Edition, Phage Lambda Revisited

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A Genetic Switch: Gene Control and Phage Lambda by Mark Ptashne

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